Pearlstein T B
Department of Psychiatry and Human Behavior, Brown University School of Medicine/Butler Hospital, Providence, RI 02906, USA.
Am J Obstet Gynecol. 1995 Aug;173(2):646-53. doi: 10.1016/0002-9378(95)90297-x.
The diagnosis, epidemiology, etiology, and treatment of premenstrual syndrome are reviewed. A relationship between depression and premenstrual syndrome is suggested by the increased prevalence of prior depressive episodes in women with premenstrual syndrome, common neurotransmitter and chronobiologic abnormalities, and the successful treatment of premenstrual syndrome with regimens used for depression. The relationship between menopause and depression is not clearly defined, but the perimenopausal years may be a time of increased depression for women who are at risk for depressive recurrences. The role of hormone replacement treatments in either ameliorating or promoting depression in menopausal women is a subject for future studies.
本文综述了经前综合征的诊断、流行病学、病因及治疗。经前综合征女性既往抑郁发作患病率增加、常见神经递质和生物钟异常，以及用于治疗抑郁症的方案对经前综合征治疗有效，提示抑郁症与经前综合征之间存在关联。绝经与抑郁症之间的关系尚不明确，但对于有抑郁复发风险的女性，围绝经期可能是抑郁加重的时期。激素替代治疗在改善或加重绝经后女性抑郁症方面的作用是未来研究的课题。
