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The GABAA receptors.

作者信息

Stephenson F A

机构信息

School of Pharmacy, University of London, U.K.

出版信息

Biochem J. 1995 Aug 15;310 ( Pt 1)(Pt 1):1-9. doi: 10.1042/bj3100001.

DOI:10.1042/bj3100001
PMID:7646429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1135846/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcee/1135846/56545de8446e/biochemj00057-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcee/1135846/c09c42008de0/biochemj00057-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcee/1135846/56545de8446e/biochemj00057-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcee/1135846/c09c42008de0/biochemj00057-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcee/1135846/56545de8446e/biochemj00057-0018-a.jpg

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Bovine gamma-aminobutyric acidA receptor sequence-specific antibodies: identification of two epitopes which are recognised in both native and denatured gamma-aminobutyric acidA receptors.
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5
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.γ-氨基丁酸（GABA）ρ1 cDNA的克隆：一种在视网膜中高度表达的GABA受体亚基。
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Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors.编码人γ-氨基丁酸A型受体α6亚基的cDNA克隆及含α6受体的药理学特性研究
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Effect of zolpidem on gamma-aminobutyric acid (GABA)-induced inhibition predicts the interaction of ethanol with GABA on individual neurons in several rat brain regions.唑吡坦对γ-氨基丁酸（GABA）诱导的抑制作用的影响预示着乙醇与GABA在大鼠多个脑区单个神经元上的相互作用。
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本文引用的文献

1
Nicotinic acetylcholine receptor at 9 A resolution.分辨率为9埃的烟碱型乙酰胆碱受体。
J Mol Biol. 1993 Feb 20;229(4):1101-24. doi: 10.1006/jmbi.1993.1107.
2
A cluster of three GABAA receptor subunit genes is deleted in a neurological mutant of the mouse p locus.在小鼠p位点的一个神经学突变体中，一组三个GABAA受体亚基基因被删除。
Nature. 1993 Jul 29;364(6436):448-50. doi: 10.1038/364448a0.
3
High-resolution mapping of the gamma-aminobutyric acid receptor subunit beta 3 and alpha 5 gene cluster on chromosome 15q11-q13, and localization of breakpoints in two Angelman syndrome patients.
印度人参水醇提取物通过调节γ-氨基丁酸/组胺受体及脑电图慢波模式改善实验模型中的睡眠。
Prev Nutr Food Sci. 2022 Mar 31;27(1):108-120. doi: 10.3746/pnf.2022.27.1.108.
4
Midazolam: an essential palliative care drug.咪达唑仑：一种重要的姑息治疗药物。
Palliat Care Soc Pract. 2020 Jan 13;14:2632352419895527. doi: 10.1177/2632352419895527. eCollection 2020.
5
A half century of γ-aminobutyric acid.γ-氨基丁酸的半个世纪
Brain Neurosci Adv. 2019 Nov 27;3:2398212819858249. doi: 10.1177/2398212819858249. eCollection 2019 Jan-Dec.
6
Triphlorethol A, a Dietary Polyphenol from Seaweed, Decreases Sleep Latency and Increases Non-Rapid Eye Movement Sleep in Mice.三苯甲醚 A，一种来自海藻的膳食多酚，可减少小鼠的睡眠潜伏期并增加非快速眼动睡眠。
Mar Drugs. 2018 Apr 24;16(5):139. doi: 10.3390/md16050139.
7
Marine polyphenol phlorotannins promote non-rapid eye movement sleep in mice via the benzodiazepine site of the GABAA receptor.海洋多酚类缩合单宁通过GABAA受体的苯二氮䓬位点促进小鼠的非快速眼动睡眠。
Psychopharmacology (Berl). 2014 Jul;231(14):2825-37. doi: 10.1007/s00213-014-3445-1. Epub 2014 Feb 1.
8
Neurochemical and behavioral features in genetic absence epilepsy and in acutely induced absence seizures.遗传性失神癫痫和急性诱发失神发作的神经化学及行为特征。
ISRN Neurol. 2013 May 7;2013:875834. doi: 10.1155/2013/875834. Print 2013.
9
Molecular imaging of microglia/macrophages in the brain.脑内小胶质细胞/巨噬细胞的分子影像学
Glia. 2013 Jan;61(1):10-23. doi: 10.1002/glia.22357. Epub 2012 May 21.
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HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes.基于高效液相色谱的活性谱分析方法，用于在非洲爪蟾卵母细胞上通过自动双微电极电压钳测定法发现GABAA受体配体。
Planta Med. 2008 Apr;74(5):521-6. doi: 10.1055/s-2008-1074491.
15号染色体q11-q13区域γ-氨基丁酸受体β3亚基和α5基因簇的高分辨率图谱绘制以及两名天使综合征患者断点的定位。
Am J Hum Genet. 1993 Jun;52(6):1216-29.
4
A point mutation in a Drosophila GABA receptor confers insecticide resistance.果蝇γ-氨基丁酸受体中的一个点突变赋予了其抗杀虫剂能力。
Nature. 1993 Jun 3;363(6428):449-51. doi: 10.1038/363449a0.
5
Comparison of interactions of [3H]muscimol, t-butylbicyclophosphoro[35S]thionate, and [3H]flunitrazepam with cloned gamma-aminobutyric acidA receptors of the alpha 1 beta 2 and alpha 1 beta 2 gamma 2 subtypes.[3H]蝇蕈醇、叔丁基双环磷[35S]硫代酸盐和[3H]氟硝西泮与α1β2和α1β2γ2亚型克隆的γ-氨基丁酸A受体相互作用的比较。
Mol Pharmacol. 1993 May;43(5):801-6.
6
GABAA receptor populations with novel subunit combinations and drug binding profiles identified in brain by alpha 5- and delta-subunit-specific immunopurification.通过α5和δ亚基特异性免疫纯化在大脑中鉴定出具有新型亚基组合和药物结合谱的GABAA受体群体。
J Biol Chem. 1993 Mar 15;268(8):5965-73.
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A strong promoter element is located between alternative exons of a gene encoding the human gamma-aminobutyric acid-type A receptor beta 3 subunit (GABRB3).一个强启动子元件位于编码人类γ-氨基丁酸A型受体β3亚基（GABRB3）的基因的可变外显子之间。
J Biol Chem. 1993 Feb 25;268(6):4420-8.
8
Further evidence for the existence of alpha subunit heterogeneity within discrete gamma-aminobutyric acidA receptor subpopulations.离散的γ-氨基丁酸A受体亚群中存在α亚基异质性的进一步证据。
J Biol Chem. 1993 Feb 15;268(5):3753-7.
9
Mutation of glycine receptor subunit creates beta-alanine receptor responsive to GABA.甘氨酸受体亚基的突变产生了对γ-氨基丁酸有反应的β-丙氨酸受体。
Science. 1993 Oct 8;262(5131):256-8. doi: 10.1126/science.8211147.
10
The subunit composition of a GABAA/benzodiazepine receptor from rat cerebellum.大鼠小脑GABAA/苯二氮䓬受体的亚基组成。
J Neurochem. 1994 Jul;63(1):371-4. doi: 10.1046/j.1471-4159.1994.63010371.x.