Christiansen C
Den Danske Forskningsfond, CCBR, Ballerup.
Ugeskr Laeger. 1993 Aug 2;155(31):2383-6.
This article reviews a number of methods for the treatment and prevention of osteoporosis. A preventive treatment achieves the best effect if it is started as soon after menopause as possible. Hormone substitution treatment has in many trials been shown to be effective in stopping the post-menopausal demineralization of the skeleton. Calcitonin is suggested as an alternative to hormone substitution, however this substance is still not registered in Denmark for this purpose. There are today several possible treatments for symptomatic osteoporosis; however, the long-term effect on frequency of new fractures remains to be confirmed. The regulation of a number of "life-style factors" such as diet and exercise is part of both the prevention and treatment of osteoporosis.
本文综述了多种治疗和预防骨质疏松症的方法。预防性治疗若能在绝经后尽早开始,则效果最佳。在许多试验中,激素替代疗法已被证明对阻止绝经后骨骼脱矿有效。降钙素被建议作为激素替代疗法的替代品,但该物质在丹麦尚未获批用于此目的。目前有几种针对症状性骨质疏松症的治疗方法;然而,其对新发骨折发生率的长期影响仍有待证实。对饮食和运动等一些“生活方式因素”的调节是骨质疏松症预防和治疗的一部分。