Prinz R A, Kaufman B H, Folk F A, Greenlee H B
Arch Surg. 1978 Apr;113(4):520-5. doi: 10.1001/archsurg.1978.01370160178031.
Between 1954 and 1975, 80 pancreaticojejunostomies were performed on 77 patients for intractable pain of chronic pancreatitis. All patients had a history of chronic alcoholism. Drainage operations done primarily for pseudocysts were excluded. Operative procedures included seven caudal pancreaticojejunostomies, 42 longitudinal pancreaticojejunostomies with splenectomy and implantation of the pancreas into the jejunum, and 31 side-to-side pancreaticojejunostomies. Eighty-one percent of the patients noted substantial improvement or complete resolution of their abdominal pain on follow-up that ranged up to 21 years. The operative mortality was 5%. Thirty-two patients died during the period of the follow-up. Continued alcohol abuse, carcinoma, and cardiovascular disease were the leading causes of mortality. Data from this review confirm the effectiveness of pancreaticojejunostomy in relieving the pain of chronic relapsing pancreatitis.
1954年至1975年间，对77例慢性胰腺炎顽固性疼痛患者实施了80例胰空肠吻合术。所有患者均有慢性酒精中毒史。主要针对假性囊肿进行的引流手术被排除在外。手术方式包括7例胰尾空肠吻合术、42例纵行胰空肠吻合术（同时行脾切除术并将胰腺植入空肠）以及31例侧侧胰空肠吻合术。81%的患者在长达21年的随访中腹痛得到显著改善或完全缓解。手术死亡率为5%。32例患者在随访期间死亡。持续酗酒、癌症和心血管疾病是主要死因。本综述的数据证实了胰空肠吻合术在缓解慢性复发性胰腺炎疼痛方面的有效性。
