Pinsolle J, Michelet V, Coustal B, Siberchicot F, Michelet F X
Department of Maxillofacial and Plastic Surgery, Centre Hospitalier Universitaire de Bordeaux, France.
Arch Otolaryngol Head Neck Surg. 1995 Sep;121(9):994-6. doi: 10.1001/archotol.1995.01890090036007.
To evaluate treatment of ameloblastoma of the jaws and suggest a more aggressive approach for well-defined cases.
Referral center.
Forty-one patients were treated for ameloblastoma of the jaws.
Seventeen patients had a local recurrence; 14 had initial curettage and three had initial resection. Seven patients had two or more recurrences. Eight patients underwent radiotherapy; two died of progressive disease.
Ameloblastoma had a high rate of local recurrence if not adequately removed. Segmental resection for the mandible and partial maxillectomy for the maxilla should be the primary treatment; marginal resection is appropriate only for small primary tumors. For multiple recurrences, radiotherapy is effective, and surgery and radiotherapy (50 Gy postoperatively) should be used in selected cases.
评估颌骨成釉细胞瘤的治疗方法，并针对明确的病例提出更积极的治疗方案。
转诊中心。
41例颌骨成釉细胞瘤患者接受了治疗。
17例患者出现局部复发；14例最初接受了刮除术，3例最初接受了切除术。7例患者复发两次或更多次。8例患者接受了放疗；2例死于疾病进展。
成釉细胞瘤若未得到充分切除，局部复发率较高。下颌骨节段性切除和上颌骨部分切除术应作为主要治疗方法；边缘性切除仅适用于小的原发性肿瘤。对于多次复发，放疗有效，在特定病例中应采用手术和放疗（术后50 Gy）。
