Rinaldi R G, Carballido J, Betancourt B, Sartori M, Almodóvar E A
Department of Cardiovascular Surgery, Pavia Heart Institute, Santurce, Puerto Rico, USA.
Tex Heart Inst J. 1995;22(2):185-8.
Systemic lupus erythematosus is an autoimmune disease that often involves the cardiovascular system. Coronary artery narrowing in patients with lupus erythematosus is severe, progressive, and related to the duration of the disease rather than to the age of the patient. Steroid use in such patients has improved their life expectancy but seems to be increasing the incidence of coronary involvement. Consequently, a larger number of systemic lupus erythematosus patients may be candidates for myocardial revascularization in the future. We report our experience with myocardial revascularization in 2 women with severe systemic lupus erythematosus, incapacitating angina, and severe obstructive coronary artery disease. One of the women required balloon angioplasty 19 months after coronary artery bypass grafting and remains asymptomatic nearly 3 years later. The other patient is free of symptoms 9 months after surgery. Our results with these 2 patients are encouraging. Long-term follow-up should yield further information regarding the benefits of myocardial revascularization and coronary angioplasty in patients with systemic lupus erythematosus.
系统性红斑狼疮是一种常累及心血管系统的自身免疫性疾病。红斑狼疮患者的冠状动脉狭窄严重、呈进行性，且与疾病持续时间有关，而非与患者年龄有关。此类患者使用类固醇改善了其预期寿命，但似乎增加了冠状动脉受累的发生率。因此，未来可能会有更多的系统性红斑狼疮患者成为心肌血运重建的候选者。我们报告了对两名患有严重系统性红斑狼疮、失能性心绞痛和严重阻塞性冠状动脉疾病的女性进行心肌血运重建的经验。其中一名女性在冠状动脉旁路移植术后19个月需要进行球囊血管成形术，近3年后仍无症状。另一名患者术后9个月无症状。我们对这两名患者的治疗结果令人鼓舞。长期随访应能提供更多关于心肌血运重建和冠状动脉血管成形术对系统性红斑狼疮患者益处的信息。
