适度能量限制饮食对非肥胖男性能量代谢和身体成分的影响。

Impact of a moderately energy-restricted diet on energy metabolism and body composition in non-obese men.

作者信息

Velthuis-te Wierik E J, Westerterp K R, van den Berg H

机构信息

TNO Nutrition and Food Research Institute, Department of Physiology and Kinetics, Zeist, Netherlands.

出版信息

Int J Obes Relat Metab Disord. 1995 May;19(5):318-24.

PMID:7647823

Abstract

OBJECTIVE

Since little information is available on the capacity of the non-obese to adapt to a moderate decrease in energy intake, the effect of a 10-week moderately energy-restricted diet (ER) on energy expenditure and body composition was studied.

DESIGN

A controlled intervention study. After a weight-maintaining run-in period of 2 weeks, the ER group received a diet that contained 9.2 MJ/day on average, i.e. 80% of the energy of their habitual diet (estimated by means of a 7-day dietary record) for the next ten weeks while the control group received the weight-maintaining diet.

SETTING

Subjects continued daily life habits and came to the Institute every evening to have dinner and to receive food for the next 24 h.

SUBJECTS

24 healthy non-obese, middle-aged men participated. Subjects were matched for age and body mass index and randomly assigned to a control group (n = 8) or an ER group (n = 16).

RESULTS

Average daily metabolic rate (ADMR, i.e. total energy expenditure), measured with doubly labeled water in eight subjects of the ER group, appeared to be 82.5% of reported energy intake resulting in an actual level of energy restriction in these eight subjects of 33% on average (range 18-42%), rather than 20%. Subjects in the ER group lost 7.4 +/- 1.7 kg; 83% of this weight loss was fat mass, 17% was fat-free mass. Subjects in the control group lost some weight too (2.1 +/- 1.5 kg). Resting metabolic rate (RMR) (MJ/day) decreased in the ER group (P < 0.001). In this group the thyroid hormone triiodothyronine (T3) decreased (P < 0.001), while reverse T3 (rT3) increased (P < 0.05). ADMR decreased significantly.

CONCLUSION

Under conditions of a controlled moderately energy-restricted diet in daily life a significant weight loss can be induced, similar to that observed after a balanced dietary deficit, providing 5 MJ/day. In addition, moderate energy restriction induces a decrease in fat-free mass and a fall in RMR.

摘要

目的

由于关于非肥胖者适应适度能量摄入减少能力的信息较少，因此研究了为期10周的适度能量限制饮食（ER）对能量消耗和身体成分的影响。

设计

一项对照干预研究。在为期2周的体重维持导入期后，ER组在接下来的十周内平均每天摄入含9.2兆焦耳能量的饮食，即其习惯饮食能量的80%（通过7天饮食记录估算），而对照组则接受维持体重的饮食。

背景

受试者保持日常生活习惯，每天晚上到研究所吃晚餐并领取接下来24小时的食物。

受试者

24名健康的非肥胖中年男性参与。受试者按年龄和体重指数匹配，随机分为对照组（n = 8）或ER组（n = 16）。

结果

用双标水法测量了ER组8名受试者的平均每日代谢率（ADMR，即总能量消耗），结果显示为报告能量摄入量的82.5%，这导致这8名受试者的实际能量限制水平平均为33%（范围为18 - 42%），而非20%。ER组的受试者体重减轻了7.4±1.7千克；体重减轻的83%为脂肪量，17%为去脂体重。对照组的受试者也减轻了一些体重（2.1±1.5千克）。ER组的静息代谢率（RMR）（兆焦耳/天）降低（P < 0.001）。在该组中，甲状腺激素三碘甲状腺原氨酸（T3）降低（P < 0.001），而反三碘甲状腺原氨酸（rT3）升高（P < 0.05）。ADMR显著降低。