Clewell D B, Flannagan S E, Jaworski D D
Dept of Biologic and Materials Sciences, School of Dentistry, School of Medicine, University of Michigan, Ann Arbor 48109, USA.
Trends Microbiol. 1995 Jun;3(6):229-36. doi: 10.1016/s0966-842x(00)88930-1.
Conjugative transposons are highly ubiquitous elements found throughout the bacterial world. Members of the Tn916-Tn1545 family carry the widely disseminated tetracycline-resistance determinant Tet M, as well as additional resistance genes. They have been found naturally in, or been introduced into, over 50 different species and 24 genera of bacteria. Recent investigations have led to insights into the molecular basis of movement of these interesting mobile elements.
接合转座子是在整个细菌界广泛存在的元件。Tn916 - Tn1545家族的成员携带广泛传播的四环素抗性决定簇Tet M以及其他抗性基因。它们已在超过50种不同的细菌物种和24个细菌属中自然发现或被引入。最近的研究已深入了解这些有趣的移动元件移动的分子基础。
