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[中国14省15岁以下儿童急性弛缓性麻痹(AFP)发病情况的流行病学分析]

[Epidemiological analysis on morbidity of acute flaccid paralysis (AFP) among children under 15 years old in 14 provinces of China].

作者信息

Zhang X L, Wang K A

机构信息

EPI Centre, Chinese Academy of Preventive Medicine, Beijing, P.R. China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1995 Dec;16(6):348-53.

PMID:8728955
Abstract

Five investigations through analysis of hospital records on morbidity of Acute Flaccid Paralysis (AFP) among children under 15 years old in 14 provinces of China have currently been conducted. In this paper, data from a series of studies published in journals or reported to meetings was combined and analyzed based on Meta-Analysis. Comparisons have been made between AFP, poliomyelitis, Guillian-Barre Syndrome (GBS) and non-polio AFP morbidities and their distributions by age, sex and month. The morbidity rates for these four categories were 1.41, 0.54, 0.55 and 1.05 per 10(5) respectively. An important conclusion drawn from of this study was that the criterion put forward by WHO, reported rate of non-polio AFP should reach over 1.0 per 10(5) among children under 15, can also be used as an indicator for sensitivity evaluation and monitoring of AFP surveillance system in China.

摘要

目前已在中国14个省份开展了五项关于15岁以下儿童急性弛缓性麻痹(AFP)发病率的医院记录分析调查。本文基于Meta分析,对发表在期刊上或在会议上报告的一系列研究数据进行了合并和分析。对AFP、脊髓灰质炎、格林-巴利综合征(GBS)和非脊髓灰质炎AFP的发病率及其按年龄、性别和月份的分布进行了比较。这四类疾病的发病率分别为每10万1.41、0.54、0.55和1.05。本研究得出的一个重要结论是,世界卫生组织提出的15岁以下儿童非脊髓灰质炎AFP报告发病率应达到每10万1.0以上的标准,也可作为中国AFP监测系统敏感性评估和监测的指标。

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