Zhang D M, Peng Z, Tian Z
Epidemic-prevention Brigade Department of Health General Logistics Department, PLA, Beijing.
Zhonghua Yu Fang Yi Xue Za Zhi. 1995 May;29(3):147-8.
Three episodes of illness outbreak, with major symptoms of acute abdominal pain and diarrhea, occurred in 1990 to 1991 in the army forces stationed in Beijing. Bacillary dysentery outbreak caused by Shigella dysentariae were confirmed with epidemiological investigations and pathogen identification. Drug sensitivity tests with Kirby-Bauer method for the strain isolated showed it had obvious resistance to 13 of 14 kinds of antibiotics tested. Detection of plasmid with Birnboim method showed most of the strains had R-plasmid of 120-140 Md and few had small plasmid. It suggested inherent connection between drug-resistance of the strains and plasmid.
1990年至1991年，驻扎在北京的部队发生了3起疾病暴发，主要症状为急性腹痛和腹泻。经流行病学调查和病原体鉴定，确诊为痢疾志贺菌引起的细菌性痢疾暴发。对分离出的菌株采用K-B法进行药敏试验，结果显示该菌株对所检测的14种抗生素中的13种有明显耐药性。采用Birnboim法检测质粒，结果显示大多数菌株有120 - 140 Md的R质粒，少数有小质粒。这表明菌株的耐药性与质粒之间存在内在联系。
