Barbut F, Leluan P, Antoniotti G, Collignon A, Sédallian A, Petit J C
Laboratoire de Microbiologie, Hôpital Saint-Antoine, Paris, France.
Eur J Clin Microbiol Infect Dis. 1995 Apr;14(4):346-9. doi: 10.1007/BF02116530.
In a prospective study conducted over a six-month period, the relative yield of 721 routine cultures of stool from adult inpatients as a function of the time after hospital admission was assessed. Salmonella, Campylobacter, Shigella or Yersinia spp. were recovered from 10.9% (41/377) of patients within three days of hospitalization and from only 1.5% (5/344) after three days. However, a review of these patients' charts did not suggest nosocomial transmission but rather a delay in stool collection or asymptomatic carriage. Clostridium difficile was isolated with a high frequency in patients both within and after three days of hospitalization (10.3% and 10.2%, respectively). Thus, stool specimens from adults hospitalized for more than three days should not be cultured except for Clostridium difficile unless there are plausible clinical or epidemiological reasons to do so.
在一项为期六个月的前瞻性研究中，评估了721份成年住院患者常规粪便培养物的相对检出率与入院后时间的关系。沙门氏菌、弯曲杆菌、志贺氏菌或耶尔森氏菌属在住院三天内从10.9%（41/377）的患者中检出，三天后仅从1.5%（5/344）的患者中检出。然而，对这些患者病历的审查并未提示医院内传播，而是提示粪便采集延迟或无症状携带。艰难梭菌在住院三天内及三天后的患者中分离频率较高（分别为10.3%和10.2%）。因此，除非有合理的临床或流行病学原因，否则住院超过三天的成人粪便标本不应进行培养，艰难梭菌除外。
