腹泻病患者中艰难梭菌的相对频率。
Relative frequency of Clostridium difficile in patients with diarrheal disease.
作者信息
Gilligan P H, McCarthy L R, Genta V M
出版信息
J Clin Microbiol. 1981 Jul;14(1):26-31. doi: 10.1128/jcm.14.1.26-31.1981.
Abstract
We have studied 161 patients with diarrheal disease to determine the frequency with which Clostridium difficile occurs in such patients. C. difficile or its toxin or both were detected in stools from 19 patients (11.9%), 17 of whom had previously received antimicrobial agents. Enteric pathogens other than C. difficile were recovered less frequently, with Salmonella sp., Giardia lamblia, and Campylobacter fetus being recovered from 4.1, 2.5, and 1.3%, respectively, of the patients studied. These data suggest that C. difficile may be frequently encountered in specimens obtained from patients with diarrhea who receive antibiotics and may play a role in diarrheal disease in such patients.
摘要
我们研究了161例腹泻病患者，以确定艰难梭菌在这类患者中的出现频率。在19例患者（11.9%）的粪便中检测到艰难梭菌或其毒素或两者皆有，其中17例患者先前接受过抗菌药物治疗。除艰难梭菌外的肠道病原体检出频率较低，分别从4.1%、2.5%和1.3%的研究患者中分离出沙门氏菌、蓝氏贾第鞭毛虫和胎儿弯曲菌。这些数据表明，在接受抗生素治疗的腹泻患者的标本中可能经常遇到艰难梭菌，并且它可能在这类患者的腹泻病中起作用。
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