Hochlowski J E, Whittern D N, Buko A, Alder L, McAlpine J B
Abbott Laboratories, Abbott Park, Illinois 60064, USA.
J Antibiot (Tokyo). 1995 Jul;48(7):614-8. doi: 10.7164/antibiotics.48.614.
Two novel antifungal compounds of the papulacandin class, named fusacandins A and B, have been isolated from Fusarium sambucinum. Each compound contains two units of galactose and one of glucose, the latter connected as a C-glycoside to an aromatic moiety. Fusacandin A is esterified at two sites with long-chain, unsaturated fatty acids and fusacandin B at only one site. The structures of the fusacandins were elucidated through analysis of mass spectral and 1-D and 2-D homonuclear and heteronuclear NMR data.
