对糖尿病基底膜的细胞免疫和循环免疫，一项阴性结果。
Cellular and circulating immunity to diabetic basement membrane, a negative finding.
作者信息
De Bats A, Park J R, Rhodes E L
出版信息
Clin Exp Immunol. 1975 Nov;22(2):316-22.
Abstract
A linear deposition of IgG was seen by immunofluorescence on the glomerular basement membrane of a diabetic kidney. However, when the remaining kidney was subjected to elution with acidic buffer the eluate had no affinity for glomerular basement membrane. The leucocytes from normal and diabetic subjects were also tested for an in vitro cell-mediated response to diabetic and normal basement membrane. No difference was found between the reaction of leucocytes from diabetics and those from normal age- and sex-matched controls.
摘要
免疫荧光检查发现糖尿病肾病的肾小球基底膜上有IgG线性沉积。然而，当用酸性缓冲液洗脱剩余肾脏时，洗脱液对肾小球基底膜没有亲和力。还对正常人和糖尿病患者的白细胞进行了体外细胞介导的对糖尿病和正常基底膜的反应测试。糖尿病患者的白细胞与年龄和性别匹配的正常对照组白细胞的反应之间未发现差异。
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