Chest. 1976 Feb;69(2):216-9.
Fiberglass inhalation seems to produce a minimal tissue response in the lungs, and the reaction is one of macrophagic mobilization and is characteristic of the pulmonary response to those nonfibrogenic dusts classified as nuisance dusts. In order to merit the designation of a nuisance dust, the pulmonary response must fulfill the following three requisites:31(p5) (1) The alveolar architecture must remain intact. (2) The stromal proliferation is minimal and consists mainly of reticulin. (3) The tissue reaction is potentially reversible. Inasmuch as the pulmonary reaction to the dusts of fiber glass fulfills all of these requirements, it should be classified as a nuisance dust. 31(p5) There is no evidence to indicate that inhaling fiber glass is associated with either permanent respiratory impairment or carcinogenesis; however, the final verdict as far as the latter is concerned must await the findings of long-term mortality studies.
吸入玻璃纤维似乎在肺部引起的组织反应极小，这种反应是巨噬细胞动员的反应之一，是肺部对那些被归类为有害粉尘的非纤维生成性粉尘反应的特征。为了符合有害粉尘的认定，肺部反应必须满足以下三个条件：31（第5页）（1）肺泡结构必须保持完整。（2）间质增生极少，主要由网状纤维组成。（3）组织反应可能是可逆的。由于肺部对玻璃纤维粉尘的反应满足所有这些要求，它应被归类为有害粉尘。31（第5页）没有证据表明吸入玻璃纤维与永久性呼吸功能损害或致癌作用有关；然而，就后者而言的最终定论必须等待长期死亡率研究的结果。
