Tai C T, Chen S A, Chiang C E, Wu T J, Cheng C C, Chiou C W, Lee S H, Ueng K C, Wang S P, Chiang B N
Department of Medicine, National Yang-Ming University, School of Medicine, Taiwan, R.O.C.
Jpn Heart J. 1995 May;36(3):305-17. doi: 10.1536/ihj.36.305.
Accessory pathway-mediated tachyarrhythmias and AV nodal reentrant tachycardia represent a large portion of supraventricular tachycardia in younger patients. Reports comparing electrophysiologic characteristics and results of radiofrequency ablation between teenagers and adults from the same electrophysiology laboratory are rare, and these deserve further study. This study included 49 teenage patients (mean age 17 +/- 3 years, range from 10 to 20) and 1008 adult patients (mean age 50 +/- 13 years, range from 21 to 92) referred for electrophysiologic study and radiofrequency ablation for treatment of accessory pathway-mediated and AV nodal reentrant tachycardia. The results showed that: (1) mean duration of tachyarrhythmia was shorter in teenagers, but incidences of syncope, cardioversion for hemodynamic compromise and associated cardiovascular diseases were similar in both groups; (2) teenagers had a higher incidence of right-sided free wall accessory pathways (34.1% vs 14.9%, p = 0.048) and better conduction properties of accessory pathways and AV nodal pathways; (3) fast-slow and multiple forms of AV nodal reentrant tachycardia were significantly less frequent (p = 0.026) in teenagers, whereas atrial fibrillation with ventricular preexcitation was common in adults; (4) success rate, incidence of recurrent tachycardia, total procedure time, radiation exposure time and number of radiofrequency pulses for successful ablation did not differ significantly between teenagers and adults.
(1) different electrophysiologic characteristics were found between teenagers and adults; and (2) radiofrequency ablation was effective and safe in teenagers with paroxysmal supraventricular tachycardia.
旁路介导的快速心律失常和房室结折返性心动过速在年轻患者的室上性心动过速中占很大比例。来自同一电生理实验室的青少年与成人之间电生理特征及射频消融结果比较的报道很少,这些值得进一步研究。本研究纳入了49例青少年患者(平均年龄17±3岁,范围10至20岁)和1008例成人患者(平均年龄50±13岁,范围21至92岁),他们因旁路介导的和房室结折返性心动过速接受电生理检查及射频消融治疗。结果显示:(1)青少年心动过速的平均持续时间较短,但两组晕厥、因血流动力学不稳定进行心脏复律及相关心血管疾病的发生率相似;(2)青少年右侧游离壁旁路发生率较高(34.1%对14.9%,p = 0.048),旁路及房室结传导特性较好;(3)青少年快慢型和多种形式的房室结折返性心动过速明显较少见(p = 0.026),而成人中预激综合征合并心房颤动常见;(4)青少年与成人在成功率、心动过速复发率、总手术时间、辐射暴露时间及成功消融所需射频脉冲数方面无显著差异。
(1)青少年与成人存在不同的电生理特征;(2)射频消融治疗青少年阵发性室上性心动过速有效且安全。