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食物延迟时间与大鼠程序性诱导多饮的发展

Food-delay duration and the development of schedule-induced polydipsia in rats.

作者信息

Lamas E, Pellón R

机构信息

Facultad de Psicología, Universidad Nacional de Educación a Distancia, Madrid, Spain.

出版信息

Physiol Behav. 1995 Jun;57(6):1221-4. doi: 10.1016/0031-9384(94)00371-b.

DOI:10.1016/0031-9384(94)00371-b
PMID:7652048
Abstract

Twelve rats were exposed to a schedule that delivered a food pellet every 60 s (fixed time 60 s). The development of schedule-induced polydipsia was measured in terms of the water consumed and the licks per interpellet interval. Every lick by master rats initiated an unsignalled delay of 2 or 50 s in food delivery. Yoked-control rats received food at the same time as their masters, being unaffected by their own licking. Schedule-induced polydipsia developed in master rats exposed to 2-s delays, but more slowly and to a lesser extent than control animals. The development of polydipsia was prevented in master rats exposed to 50-s delays, however. When these delays were discontinued, polydipsia was obtained by master rats. The finding that the effect of the delays was modulated by their duration supports the view that the development of schedule-induced polydipsia is sensitive to control by its environmental consequences.

摘要

将12只大鼠置于一种每隔60秒给予一粒食物丸的程序安排下(固定时间为60秒)。根据饮水量和每次食物丸间隔期间的舔舐次数来测量程序诱导的过度饮水行为的发展情况。主试大鼠的每次舔舐都会引发食物递送2秒或50秒的无信号延迟。被配对的对照大鼠与它们的主试大鼠同时获得食物,不受自身舔舐行为的影响。在经历2秒延迟的主试大鼠中出现了程序诱导的过度饮水行为,但比对照动物发展得更慢且程度更低。然而,在经历50秒延迟的主试大鼠中,过度饮水行为的发展受到了抑制。当这些延迟停止后,主试大鼠出现了过度饮水行为。延迟的效果受其持续时间调节这一发现支持了这样一种观点,即程序诱导的过度饮水行为的发展对其环境后果的控制很敏感。

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