Lucker G P, van de Kerkhof P C, Cruysberg J R, der Kinderen D J, Steijlen P M
Department of Dermatology, University Hospital, Nijmegen, The Netherlands.
Dermatology. 1995;190(4):292-4. doi: 10.1159/000246719.
Two patients with Sjögren-Larsson syndrome were treated with calcipotriol in ointment and the ointment base only for 12 weeks, using a double-blind bilaterally paired comparative study. Unilateral improvement was observed in both patients in favour of the calcipotriol-treated side. The present case is the first demonstration of a substantial clinical effect of calcipotriol in the Sjögren-Larsson syndrome.
采用双盲双侧配对对照研究,对两名舍格伦-拉松综合征患者分别使用骨化三醇软膏和单纯软膏基质进行为期12周的治疗。两名患者均出现单侧改善,且均为使用骨化三醇治疗的一侧效果更佳。本病例首次证明了骨化三醇对舍格伦-拉松综合征具有显著的临床疗效。