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静脉血栓栓塞症的溶栓治疗。临床试验与当前适应症。

Thrombolytic therapy in venous thromboembolism. Clinical trials and current indications.

作者信息

Goldhaber S Z

机构信息

Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Clin Chest Med. 1995 Jun;16(2):307-20.

PMID:7656542
Abstract

Thrombolytic therapy for venous thromboembolism is returning, especially for the management of acute pulmonary embolism patients who present with either hypotension or with right ventricular dysfunction despite an initially normal blood pressure and heart rate. Clinicians have learned to use thrombolysis to improve efficacy, minimize bleeding complications, and achieve savings in cost. The objective of therapy is rapid reversal of right ventricular dysfunction, which might otherwise lead to intractable right ventricular failure and death.

摘要

静脉血栓栓塞症的溶栓治疗正在回归,尤其是用于治疗急性肺栓塞患者,这些患者要么出现低血压,要么尽管初始血压和心率正常,但存在右心室功能障碍。临床医生已学会使用溶栓疗法来提高疗效、将出血并发症降至最低并节省成本。治疗的目标是迅速逆转右心室功能障碍,否则可能会导致难治性右心室衰竭和死亡。

相似文献

1
Thrombolytic therapy in venous thromboembolism. Clinical trials and current indications.静脉血栓栓塞症的溶栓治疗。临床试验与当前适应症。
Clin Chest Med. 1995 Jun;16(2):307-20.
2
Thrombolytic therapy for venous thromboembolism. Complications and contraindications.静脉血栓栓塞症的溶栓治疗。并发症与禁忌证。
Clin Chest Med. 1995 Jun;16(2):321-8.
3
Is thrombolytic therapy effective for pulmonary embolism?溶栓治疗对肺栓塞有效吗?
Am Fam Physician. 2002 Mar 15;65(6):1097-102.
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The current role of thrombolytic therapy for pulmonary embolism.
Semin Vasc Surg. 2000 Sep;13(3):217-20.
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Thrombolytic therapy for patients with pulmonary embolism who are hemodynamically stable but have right ventricular dysfunction: pro.对血流动力学稳定但有右心室功能障碍的肺栓塞患者进行溶栓治疗:支持。
Arch Intern Med. 2005 Oct 24;165(19):2197-9; discussion 2204-5. doi: 10.1001/archinte.165.19.2197.
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Thrombolysis for pulmonary embolism in patients with right ventricular dysfunction: con.右心室功能不全患者肺栓塞的溶栓治疗:结论
Arch Intern Med. 2005 Oct 24;165(19):2200-3; discussion 2204-5. doi: 10.1001/archinte.165.19.2200.
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Thrombolysis compared with heparin for the initial treatment of pulmonary embolism: a meta-analysis of the randomized controlled trials.溶栓与肝素用于肺栓塞初始治疗的比较:随机对照试验的荟萃分析
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引用本文的文献

1
The effect of the fibrinolytic enzyme FIIa from Agkistrodon acutus venom on acute pulmonary thromboembolism.尖吻蝮蛇纤溶酶 FIIa 对急性肺血栓栓塞症的影响。
Acta Pharmacol Sin. 2011 Feb;32(2):239-44. doi: 10.1038/aps.2010.193.
2
Prevention and treatment of venous thromboembolism.静脉血栓栓塞症的预防与治疗。
Drugs. 1996 Jul;52(1):71-92. doi: 10.2165/00003495-199652010-00006.