Lou H, Wu R, Fu Y
Zhejiang Cancer Hospital, Hangzhou.
Zhonghua Zhong Liu Za Zhi. 1995 Mar;17(2):112-4.
Selenium (Se) concentration in serum, hair, normal cervix tissue or tissue of cervix cancer of 20 cases with cancer of uterine cervix (survey group), 21 with myoma of the uterus and 1 with cervical polys (control group), but also in rice, water and soil in the high and low incidence areas of cervical cancer was determined. The results showed that Se concentration in serum and cancer tissue of uterine cervix in patients with cancer of uterine cervix was significantly lower than that in the control group (P < 0.05), but no significant difference of Se concentration in hair was observed (P > 0.05), However Se concentration in rice, water and soil in the high incidence areas of cervical cancer was significantly lower than that in the low incidence areas (P < 0.05). Se deficiency may play a role in the carcinogenesis of uterine cervix.
测定了20例宫颈癌患者（观察组）、21例子宫肌瘤患者和1例宫颈息肉患者（对照组）血清、头发、正常宫颈组织及宫颈癌组织中的硒（Se）含量，同时还测定了宫颈癌高低发区大米、水及土壤中的硒含量。结果显示，宫颈癌患者血清及宫颈组织中的硒含量显著低于对照组（P<0.05），但头发中的硒含量无显著差异（P>0.05）。然而，宫颈癌高发区大米、水及土壤中的硒含量显著低于低发区（P<0.05）。硒缺乏可能在宫颈癌的发生过程中起作用。
