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骨质疏松症。临床特征、预防与治疗。

Osteoporosis. Clinical features, prevention, and treatment.

作者信息

Gambert S R, Schultz B M, Hamdy R C

机构信息

Department of Medicine, New York Medical College, Valhalla, USA.

出版信息

Endocrinol Metab Clin North Am. 1995 Jun;24(2):317-71.

PMID:7656894
Abstract

Osteoporosis is a significant and growing problem among the elderly. Although therapies exist to treat established disease, preventive measures that maintain bone mass throughout life are preferable. Osteoporosis is a condition resulting in an increased risk of skeletal fractures owing to a reduction in the volume of bone tissue. There is a preservation of the normal ratio of unmineralized-to-mineralized bone matrix. This disease affects postmenopausal women most frequently, and a link clearly exists between estrogen deficiency and accelerated bone loss. Diet, exercise, and other forms of treatment exist for well-established disease.

摘要

骨质疏松症在老年人中是一个严重且日益突出的问题。尽管有治疗已确诊疾病的疗法,但终生维持骨量的预防措施更为可取。骨质疏松症是一种由于骨组织体积减少而导致骨骼骨折风险增加的病症。未矿化骨基质与矿化骨基质的正常比例得以保留。这种疾病最常影响绝经后女性,雌激素缺乏与骨质流失加速之间显然存在关联。对于已确诊的疾病,有饮食、运动及其他形式的治疗方法。

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