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阴茎癌:基于原发灶组织学分级和浸润深度,早期区域淋巴结清扫术可提高生存率。

Carcinoma of the penis: improved survival by early regional lymphadenectomy based on the histological grade and depth of invasion of the primary lesion.

作者信息

McDougal W S

机构信息

Department of Urology, Massachusetts General Hospital, Boston.

出版信息

J Urol. 1995 Oct;154(4):1364-6. doi: 10.1016/s0022-5347(01)66863-0.

DOI:10.1016/s0022-5347(01)66863-0
PMID:7658539
Abstract

PURPOSE

This study was performed to validate a new staging system and support the concept of early regional lymphadenectomy based on this system.

MATERIALS AND METHODS

A total of 76 cases from 4 teaching hospitals was reviewed.

RESULTS

Of 24 patients with well or moderately differentiated noninvasive primary tumors 1 had regional metastases compared to 43 of 52 patients with poorly differentiated or invasive tumors.

CONCLUSIONS

By classifying disease according to the depth of invasion and degree of differentiation of the primary lesions a high degree of accuracy could be obtained in predicting the likelihood of positive groin nodes. Removing groin nodes that are microscopically positive improves the survival rate over that of delayed lymphadenectomy.

摘要

目的

本研究旨在验证一种新的分期系统,并支持基于该系统的早期区域淋巴结清扫的概念。

材料与方法

回顾了4家教学医院的76例病例。

结果

24例高分化或中分化非浸润性原发性肿瘤患者中,1例有区域转移,而52例低分化或浸润性肿瘤患者中有43例有区域转移。

结论

根据原发性病变的浸润深度和分化程度对疾病进行分类,在预测腹股沟淋巴结阳性的可能性方面可获得高度准确性。切除显微镜下阳性的腹股沟淋巴结比延迟淋巴结清扫能提高生存率。

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Carcinoma of the penis: improved survival by early regional lymphadenectomy based on the histological grade and depth of invasion of the primary lesion.阴茎癌:基于原发灶组织学分级和浸润深度,早期区域淋巴结清扫术可提高生存率。
J Urol. 1995 Oct;154(4):1364-6. doi: 10.1016/s0022-5347(01)66863-0.
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