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吸入氟尼缩松治疗特发性肺含铁血黄素沉着症。

Treatment of idiopathic pulmonary hemosiderosis with inhaled flunisolide.

作者信息

Tutor J D, Eid N S

机构信息

Department of Pediatrics, University of Louisville, Ky, USA.

出版信息

South Med J. 1995 Sep;88(9):984-6. doi: 10.1097/00007611-199509000-00021.

Abstract

Idiopathic pulmonary hemosiderosis (IPH), a rare clinical entity, is characterized by bleeding into the alveoli and progressive pulmonary fibrosis. It is usually treated with systemic corticosteroids during acute bleeding episodes and with prolonged courses of oral corticosteroids and/or other immunosuppressant drugs for maintenance therapy. Because prolonged treatment with these agents is frequently associated with significant side effects, favorable response to inhaled corticosteroids would be ideal in this condition. We report the case of a patient with IPH successfully treated with inhaled flunisolide.

摘要

特发性肺含铁血黄素沉着症(IPH)是一种罕见的临床病症,其特征为肺泡出血和进行性肺纤维化。在急性出血发作期间,通常使用全身性皮质类固醇进行治疗,而在维持治疗中则使用长时间疗程的口服皮质类固醇和/或其他免疫抑制药物。由于长期使用这些药物常常会伴随明显的副作用,因此在这种情况下,吸入性皮质类固醇产生良好反应将是理想的治疗方法。我们报告了一例使用吸入性氟尼缩松成功治疗的IPH患者的病例。

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