Basher A W, Roberts S M
Department of Clinical Sciences, College of Veterinary Medicine, Colorado State University, Fort Collins, USA.
Vet Clin North Am Small Anim Pract. 1995 May;25(3):661-76. doi: 10.1016/s0195-5616(95)50061-0.
Cataracts form in diabetic dogs because of the disruption of normal lens metabolism. The pathophysiology seems to be a combination of increased lens cell membrane permeability, reduced cell membrane function, damage from accumulating osmotic products (polyols), glycosylation of lens proteins, and oxidative injury. Lens-induced uveitis must be recognized and managed in presurgical preparation of dogs with diabetes cataracts. Phacoemulsification is the current treatment of choice for diabetic cataracts in dogs and can be performed at an earlier time than traditional extracapsular lens extraction. This may allow for greater success rates after surgery.
糖尿病犬白内障的形成是由于正常晶状体代谢受到干扰。其病理生理学似乎是晶状体细胞膜通透性增加、细胞膜功能降低、渗透性产物（多元醇）积累造成的损害、晶状体蛋白糖基化以及氧化损伤共同作用的结果。在患有糖尿病性白内障的犬术前准备中，必须认识并处理晶状体诱导的葡萄膜炎。超声乳化术是目前治疗犬糖尿病性白内障的首选方法，且可在比传统囊外晶状体摘除术更早的时间进行。这可能会使术后成功率更高。
