Ouvińa G, Perazzo J C, Di Carlo M, Negri G, Lago N, Lemberg A, Bengochea L
Cátedra de Fisiopatología, Facultad de Farmacia y Bioquímica Universidad de Buenos Aires, Argentina.
Acta Gastroenterol Latinoam. 1995;25(1):17-20.
The aim of the present paper is to determine the effect of Paracetamol (P) acute intoxication in cholestatic rats. Four groups of animals were considered: controls, controls intoxicated with P, rats intoxicated with P and cholestatic rats. Hepatic biochemical tests and liver histology were performed in every group. It is concluded that cholestatic rats intoxicated with P showed less Liver damage than in control groups.
本文的目的是确定对乙酰氨基酚（P）急性中毒对胆汁淤积性大鼠的影响。研究考虑了四组动物：对照组、P中毒对照组、P中毒大鼠组和胆汁淤积性大鼠组。对每组动物都进行了肝脏生化检测和肝脏组织学检查。结果表明，P中毒的胆汁淤积性大鼠肝脏损伤程度低于对照组。
