Wagenhäuser F J, Narozna H
Schweiz Med Wochenschr. 1975 May 17;105(20):652-8.
The new antirheumatic agent diclofenac sodium (Voltaren) has been compared with indometacin with respect to tolerance and effect on osteoarthritic symptoms. In a double blind trial two groups of 30 arthritic patients each received Voltaren and indometacin respectively for 12 weeks. The initial dose for both drugs was 75 mg per day. Where the effect was inadequate the dose could be raised to 125 mg daily. The outcome revealed no significant differences of the effect and tolerance between the two drugs. An earlier onset of effect, however, was observed in the Voltaren group.
新型抗风湿药双氯芬酸钠（扶他林）在耐受性以及对骨关节炎症状的疗效方面已与吲哚美辛作了比较。在一项双盲试验中，两组各30名关节炎患者分别服用扶他林和吲哚美辛，为期12周。两种药物的初始剂量均为每日75毫克。若疗效不佳，剂量可增至每日125毫克。结果显示，两种药物在疗效和耐受性方面无显著差异。然而，扶他林组的起效时间更早。
