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膝关节激光滑膜切除术。关节手术新方法的实验结果。

Laser synovectomy of the knee joint. Experimental results on a new approach to joint surgery.

作者信息

Raunest J, Derra E

机构信息

Abteilung für Allgemein-und Unfallchirurgie, Heinrich-Heine-Universität Düsseldorf, Germany.

出版信息

Arch Orthop Trauma Surg. 1995;114(4):220-5. doi: 10.1007/BF00444267.

Abstract

The clinical impact of laser-assisted synovectomy was investigated in a two-part study consisting of a morphological part with morphometric measurements and an in vivo part using an animal model. A continuous wave Nd:YAG laser (lambda = 1064 nm; power density 18-106 W/mm2; exposure 0.5-5 s) and a XeCl excimer laser (lambda = 308 nm; pulsewidth 20 ns; repetition rate 10-70 Hz; energy density 20-45 mJ/mm2; exposure 10-60 s) were employed in combination with a fused silica fiber with diameters of 600 microns and 800 microns, respectively. In vitro study. Under light microscopy, synovium exposed to Nd:YAG laser energy presents a transitional band (with a mean diameter of 2 mm) with three zones: a carbonized area, a vesicular zone, and a coagulated part. In contrast, pulsed UV-laser irradiation leads only to a narrow transitional zone extending 10-70 microns. Scanning electron microscopy reveals a clear-cut surface following excimer synovectomy, whereas Nd:YAG laser irradiation forms an irregular surface with numerous bursts due to vaporizing activity. In vivo study. Partial synovectomy of the knee joint was performed in two groups of 14 New Zealand white rabbits with a 1064-nm Nd:YAG laser and a 308-nm XeCl excimer laser. Another 14 animals synovectomized in a conventional technique served as a control. Morphological examination and histopathological scoring of the synovial membrane were performed 4 days to 6 months after the operation. The progress of synovial regeneration following excimer laser synovectomy did not differ from observations in the control group.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在一项分为两部分的研究中,对激光辅助滑膜切除术的临床影响进行了调查,该研究包括一个进行形态测量的形态学部分和一个使用动物模型的体内部分。使用了连续波Nd:YAG激光(波长 = 1064 nm;功率密度18 - 106 W/mm²;照射时间0.5 - 5 s)和XeCl准分子激光(波长 = 308 nm;脉宽20 ns;重复频率10 - 70 Hz;能量密度20 - 45 mJ/mm²;照射时间10 - 60 s),分别与直径为600微米和800微米的熔融石英光纤联合使用。体外研究。在光学显微镜下,暴露于Nd:YAG激光能量的滑膜呈现出一个过渡带(平均直径为2毫米),有三个区域:碳化区、囊泡区和凝固部分。相比之下,脉冲紫外激光照射仅导致一个延伸10 - 70微米的狭窄过渡区。扫描电子显微镜显示准分子滑膜切除术后表面清晰,而Nd:YAG激光照射形成一个不规则表面,由于汽化活动有许多爆裂。体内研究。对两组各14只新西兰白兔分别用1064纳米的Nd:YAG激光和308纳米的XeCl准分子激光进行膝关节部分滑膜切除术。另外14只采用传统技术进行滑膜切除的动物作为对照。在术后4天至6个月对滑膜进行形态学检查和组织病理学评分。准分子激光滑膜切除术后滑膜再生的进展与对照组的观察结果没有差异。(摘要截短至250字)

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