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Comparative testicular toxicities of two isomers of dichloropropanol, 2,3-dichloro-1-propanol, and 1,3-dichloro-2-propanol, and their metabolites alpha-chlorohydrin and epichlorohydrin, and the potent testicular toxicant 1,2-dibromo-3-chloropropane.

作者信息

Omura M, Hirata M, Zhao M, Tanaka A, Inoue N

机构信息

Department of Hygiene, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Bull Environ Contam Toxicol. 1995 Jul;55(1):1-7. doi: 10.1007/BF00212381.

DOI:10.1007/BF00212381
PMID:7663078
Abstract
摘要

相似文献

1
Comparative testicular toxicities of two isomers of dichloropropanol, 2,3-dichloro-1-propanol, and 1,3-dichloro-2-propanol, and their metabolites alpha-chlorohydrin and epichlorohydrin, and the potent testicular toxicant 1,2-dibromo-3-chloropropane.二氯丙醇的两种异构体（2,3-二氯-1-丙醇和1,3-二氯-2-丙醇）及其代谢产物α-氯醇和环氧氯丙烷，以及强效睾丸毒物1,2-二溴-3-氯丙烷的比较性睾丸毒性。
Bull Environ Contam Toxicol. 1995 Jul;55(1):1-7. doi: 10.1007/BF00212381.
2
The comparative effects of 1,2-dibromo-3-chloropropane (DBCP) and its metabolites, 3-chloro-1,2-propaneoxide (epichlorohydrin), 3-chloro-1,2-propanediol (alphachlorohydrin), and oxalic acid, on the urogenital system of male rats.
Toxicol Appl Pharmacol. 1983 Aug;70(1):67-86. doi: 10.1016/0041-008x(83)90180-1.
3
Effects of alpha-chlorohydrin on the testes and epididymides of dog: a preliminary study.α-氯醇对犬睾丸和附睾的影响：一项初步研究。
Fertil Steril. 1975 Aug;26(8):781-5. doi: 10.1016/s0015-0282(16)41292-6.
4
Reproductive toxicology. 1-Chloro-2-propanol.生殖毒理学。1-氯-2-丙醇。
Environ Health Perspect. 1997 Feb;105 Suppl 1(Suppl 1):291-2.
5
Acute toxicity of 1,2-dibromo-3-chloropropane in the F344 male rat. II. Development and repair of the renal, epididymal, testicular, and hepatic lesions.
Toxicol Appl Pharmacol. 1981 Jun 15;59(1):84-95. doi: 10.1016/0041-008x(81)90455-5.
6
Involvement of cytochrome P4502E1 in the toxicity of dichloropropanol to rat hepatocyte cultures.细胞色素P4502E1参与二氯丙醇对大鼠肝细胞培养物的毒性作用。
Toxicology. 1997 Mar 28;118(2-3):171-9. doi: 10.1016/s0300-483x(96)03604-9.
7
Reproductive toxicology. Phenolphthalein.生殖毒理学。酚酞。
Environ Health Perspect. 1997 Feb;105 Suppl 1(Suppl 1):335-6.
8
Evaluation of a testicular sperm head counting technique using rats exposed to dimethoxyethyl phthalate (DMEP), glycerol alpha-monochlorohydrin (GMCH), epichlorohydrin (ECH), formaldehyde (FA), or methyl methanesulphonate (MMS).使用暴露于邻苯二甲酸二甲氧基乙酯（DMEP）、甘油α-一氯醇（GMCH）、环氧氯丙烷（ECH）、甲醛（FA）或甲磺酸甲酯（MMS）的大鼠评估一种睾丸精子头部计数技术。
Arch Toxicol. 1983 May;53(1):71-8. doi: 10.1007/BF01460003.
9
The effect of L-acetylcarnitine on some reproductive functions in the oligoasthenospermic rat.L-乙酰肉碱对少弱精子症大鼠某些生殖功能的影响。
Horm Metab Res. 1990 Dec;22(12):622-6. doi: 10.1055/s-2007-1004988.
10
Chemical sterilization of male langurs: synergistic action of alpha-chlorohydrin (U-5897) with methallibure (ICI, 33828) on the testes and epididymides of Presbytis entellus entellus Dufresne.
Endokrinologie. 1977 Jul;69(2):157-63.

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Submassive hepatic necrosis induced by dichloropropanol.二氯丙醇所致的亚大块肝坏死
Liver. 1993 Jun;13(3):123-9. doi: 10.1111/j.1600-0676.1993.tb00618.x.
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Epidemiological assessment of occupationally related, chemically induced sperm count suppression.职业相关化学物质诱导精子计数抑制的流行病学评估
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A direct effect of alpha-chlorohydrin on rat epididymal spermatozoa.
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在恶臭假单胞菌 MC4 中利用 2,3-二氯-1-丙醇的新型脱卤酶机制。
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Isolation and characterization of 2,3-dichloro-1-propanol-degrading rhizobia.降解2,3-二氯-1-丙醇的根瘤菌的分离与鉴定
Appl Environ Microbiol. 2000 Jul;66(7):2882-7. doi: 10.1128/AEM.66.7.2882-2887.2000.
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The comparative effects of 1,2-dibromo-3-chloropropane (DBCP) and its metabolites, 3-chloro-1,2-propaneoxide (epichlorohydrin), 3-chloro-1,2-propanediol (alphachlorohydrin), and oxalic acid, on the urogenital system of male rats.
Toxicol Appl Pharmacol. 1983 Aug;70(1):67-86. doi: 10.1016/0041-008x(83)90180-1.
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An extragonadal male antifertility agent.
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Effects of epichlorohydrin on male and female reproduction in Long-Evans rats.环氧氯丙烷对长 Evans 大鼠雄性和雌性生殖的影响。
Fundam Appl Toxicol. 1989 Jul;13(1):16-25. doi: 10.1016/0272-0590(89)90303-5.
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Dose dependent effects of inhaled ethylene oxide on spermatogenesis in rats.吸入环氧乙烷对大鼠精子发生的剂量依赖性影响。
Br J Ind Med. 1991 Apr;48(4):270-4. doi: 10.1136/oem.48.4.270.
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Identification and quantitative analysis of urinary metabolites of dichloropropanols in rats.大鼠体内二氯丙醇尿液代谢物的鉴定与定量分析
J UOEH. 1992 Mar 1;14(1):13-22. doi: 10.7888/juoeh.14.13.
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Resolution and some properties of enzymes involved in enantioselective transformation of 1,3-dichloro-2-propanol to (R)-3-chloro-1,2-propanediol by Corynebacterium sp. strain N-1074.棒状杆菌属菌株N-1074将1,3-二氯-2-丙醇对映选择性转化为(R)-3-氯-1,2-丙二醇过程中所涉及酶的拆分及某些性质
J Bacteriol. 1992 Dec;174(23):7613-9. doi: 10.1128/jb.174.23.7613-7619.1992.
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Infertility in male pesticide workers.男性农药工人的不育问题。
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