Lurie E, Soloviova A, Alyabieva T, Kaplun A, Panchenko L, Shvets V
M.V. Lomonosov Institute of Fine Chemical Technology, Moscow 117571, Russia.
Biochem Mol Biol Int. 1995 May;36(1):13-9.
Effect of novel aromatic GABA derivative (AFA) on lipid peroxidation (LP) was studied in the male rats of the Wistar strain. The morphine-received animals had the higher level of LP in blood plasma, decreased level of total antioxidant activity, the increased rate of LP in the ascorbate-induced system in liver homogenate. In the case of AFA administration with morphine, all the above mentioned effects were almost withdrawn.
研究了新型芳香族γ-氨基丁酸衍生物（AFA）对Wistar品系雄性大鼠脂质过氧化（LP）的影响。接受吗啡的动物血浆中LP水平较高，总抗氧化活性水平降低，肝匀浆中抗坏血酸诱导系统的LP速率增加。在AFA与吗啡联合给药的情况下，上述所有影响几乎都消失了。
