职业性暴露于辐射人群中甲状腺结节的风险：一项横断面研究。
Risk of thyroid nodules in subjects occupationally exposed to radiation: a cross sectional study.
作者信息
Antonelli A, Silvano G, Bianchi F, Gambuzza C, Tana L, Salvioni G, Baldi V, Gasperini L, Baschieri L
机构信息
Institute of Clinical Medicine II, University of Pisa, Italy.
出版信息
Occup Environ Med. 1995 Aug;52(8):500-4. doi: 10.1136/oem.52.8.500.
OBJECTIVES
To examine, by ultrasonography the prevalence of thyroid nodules in a cross sectional study of male medical workers occupationally exposed to chi radiation at the Pisa hospital, in comparison with controls matched for age and sex.
METHODS
50 male medical workers exposed to radiation were randomly matched for age (+/- 2 years) with 100 male workers not occupationally exposed to ionising radiation who lived in a slightly iodine deficient area of Tuscany (Lunigiana) (control group 1), and with 100 male workers not exposed to radiation who lived in the same area (Pisa) (control group 2).
RESULTS
Of the occupationally exposed subjects, thyroid nodules were detected in 19/50 (38.0%). Among controls, thyroid nodules were detected in 19/100 subjects of control group 1 and in 13/100 of control group 2. Comparison of exposed and control groups, stratified into 30-39, 40-49, and 50-59 year old age subgroups, showed a higher significant relative risk for thyroid nodules in the exposed subjects.
CONCLUSION
The results suggest that occupational exposure to radiation may be a risk factor for thyroid nodules.
目的
在一项横断面研究中，通过超声检查对比在比萨医院职业性接触χ射线的男性医务工作者与年龄和性别相匹配的对照组中甲状腺结节的患病率。
方法
50名职业性接触辐射的男性医务工作者按年龄（±2岁）与100名居住在托斯卡纳轻度碘缺乏地区（卢尼贾纳）的非职业性接触电离辐射的男性工作者（对照组1）以及100名居住在同一地区（比萨）的非接触辐射男性工作者（对照组2）进行随机匹配。
结果
在职业性接触辐射的受试者中，19/50（38.0%）检测到甲状腺结节。在对照组中，对照组1的100名受试者中有19名检测到甲状腺结节，对照组2的100名受试者中有13名检测到甲状腺结节。将暴露组和对照组按30 - 39岁、40 - 49岁和50 - 59岁年龄亚组分层比较，结果显示暴露组甲状腺结节的相对风险显著更高。
结论
结果表明职业性接触辐射可能是甲状腺结节的一个风险因素。
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