Cloning and sequencing of a cDNA encoding the canine HSP27 protein.
作者信息
Larsen J K, Gerthoffer W T, Hickey E, Weber L A
机构信息
Department of Pharmacology, University of Nevada School of Medicine, Reno, USA.
出版信息
Gene. 1995 Aug 19;161(2):305-6. doi: 10.1016/0378-1119(95)00290-m.
PMID:7665102
Abstract
The nucleotide (nt) sequence encoding a 27-kDa heat-shock protein (HSP27) was determined from cDNAs cloned from a canine smooth muscle library. The primary structure deduced from the nt sequence reveals a 209-amino-acid protein having 86-89% identity with human, mouse, rat and hamster small HSP. Similar to human HSP27, the canine protein contains three Ser residues that are potential MAPKAP kinase II substrates.
摘要
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