Hirschmüller A
Institut für Geschichte der Medizin, Tübingen.
Gesnerus. 1995;52(1-2):116-32.
Documents from the archives of the pharmaceutical company, E. Merck, Darmstadt, shed light on research, production, and marketing of cocaine and other coca alkaloids. When cocaine proved to be a local anaesthetic in 1884 the market expanded enormously. The production of E. Merck is compared with that of other companies in Germany and abroad. Freud, who published on cocaine from 1884 to 1887, was in contact with E. Merck and performed clinical studies for them as well as for an American company.
来自达姆施塔特的默克制药公司档案中的文件,揭示了可卡因和其他古柯生物碱的研究、生产和营销情况。1884年,可卡因被证明是一种局部麻醉剂,市场因此大幅扩张。默克公司的产量与德国国内外其他公司的产量进行了比较。弗洛伊德在1884年至1887年发表了关于可卡因的文章,他与默克公司有联系,并为该公司以及一家美国公司进行了临床研究。