大肠杆菌pfl操纵子的启动子7是ArcA对厌氧表达调控的主要决定因素。
Promoter 7 of the Escherichia coli pfl operon is a major determinant in the anaerobic regulation of expression by ArcA.
作者信息
Drapal N, Sawers G
机构信息
Lehrstuhl für Mikrobiologie, Universität München, Germany.
出版信息
J Bacteriol. 1995 Sep;177(18):5338-41. doi: 10.1128/jb.177.18.5338-5341.1995.
Abstract
The anaerobically inducible pfl operon of Escherichia coli has a regulatory sequence comprising 494 bp, which includes two anaerobically regulated promoters, termed P6 and P7. In this study, we show that in its normal context the activity of P7 is constrained and that one important function of the promoter is to mediate controlled ArcA-dependent regulation of the operon.
摘要
大肠杆菌的厌氧诱导型pfl操纵子有一个包含494个碱基对的调控序列，其中包括两个厌氧调控的启动子，称为P6和P7。在本研究中，我们表明，在其正常情况下，P7的活性受到限制，并且该启动子的一个重要功能是介导对该操纵子的可控的ArcA依赖性调控。
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