Badger J L, Miller V L
Department of Microbiology and Molecular Genetics, University of California, Los Angeles 90095, USA.
J Bacteriol. 1995 Sep;177(18):5370-3. doi: 10.1128/jb.177.18.5370-5373.1995.
rpoS, a gene that encodes an alternative sigma factor (also known as katF), is critical for the ability of Yersinia enterocolitica grown at 37 degrees C, but not at 26 degrees C, to survive diverse environmental insults such as high temperature, hydrogen peroxide, osmolarity, and low pH. However, a Y. enterocolitica rpoS mutant was not affected in expression of inv or ail, invasion of tissue culture cells, or virulence in mice.
rpoS基因编码一种替代西格玛因子(也称为katF),对小肠结肠炎耶尔森菌在37摄氏度而非26摄氏度生长时,抵抗多种环境应激(如高温、过氧化氢、渗透压和低pH值)的能力至关重要。然而,小肠结肠炎耶尔森菌的rpoS突变体在inv或ail的表达、对组织培养细胞的侵袭或对小鼠的毒力方面没有受到影响。