Radley A S, Hall J, Farrow M, Carey P J
Pharmacy Department, Sunderland District General Hospital.
J Clin Pathol. 1995 Jun;48(6):545-7. doi: 10.1136/jcp.48.6.545.
To compare the quality of outpatient anticoagulant control before and after the transfer of dosing responsibility to designated trained pharmacists from rotating junior medical staff.
All International Normalised Ratio (INR) values for an eight month period either side of the staff changeover were assessed for precision of therapeutic control according to described standards. Allowing for patient associated effects, observed and expected frequencies of "successful" control for the two staff groups were compared under the hypothesis of no association.
INR results (n = 2219) for 382 patients were analysed. For patients in stable therapeutic control, there was no significant difference in performance between the two staff groups. Patients with an INR result "out" of control limits were more likely to be returned "in" to control at their next visit by the pharmacists than by the doctors.
The quality of anticoagulant control in outpatient clinics benefits from dedicated trained staff using standard protocols.
比较将剂量调整责任从轮转的初级医务人员转移至指定的经过培训的药剂师前后门诊抗凝控制的质量。
根据既定标准,对人员交接前后八个月期间的所有国际标准化比值(INR)值进行治疗控制精度评估。考虑到患者相关影响因素,在无关联假设下比较两组工作人员“成功”控制的观察频率和预期频率。
分析了382例患者的INR结果(n = 2219)。对于处于稳定治疗控制的患者,两组工作人员的表现无显著差异。INR结果超出控制范围的患者,相较于医生,药剂师使其下次就诊时恢复到控制范围内的可能性更大。
门诊抗凝控制质量受益于使用标准方案的专业培训人员。