Kuehn R L, Berlin K D, Hawkins W E, Ostrander G K
Department of Zoology, Oklahoma State University, Stillwater 74078, USA.
J Toxicol Environ Health. 1995 Sep;46(1):101-16. doi: 10.1080/15287399509532020.
Water, sediment, and fish were sampled from three streams that were receiving or had received effluents from oil refineries. Water and sediment samples were analyzed by gas chromatography/mass spectrometry. Each stream contained aromatic carbons including substituted benzenes and naphthalenes, which are related to oil refinery operations. Fish were identified, counted, and examined for external lesions. Lengths and weights were recorded for older bullhead catfish, and their livers were examined histologically. Differences were seen in the diversity and abundance of fish among the upstream, impacted (effluent-receiving), and downstream stations. In one stream, differences in liver pathology were observed between reference bullhead, collected from an upstream station, and those collected at impacted stations with more than 50% of the bullheads taken from impacted stations having some sort of pathological change, including one with a liver clear-cell focus, which is considered a preneoplastic lesion in rodents. These data suggest a correlation between contamination of water and sediments with aromatic hydrocarbons, presumably from refinery effluents, and compromised fish health.
从三条接收或曾接收炼油厂废水的溪流中采集了水、沉积物和鱼类样本。水和沉积物样本通过气相色谱/质谱联用仪进行分析。每条溪流都含有芳香烃，包括取代苯和萘，这些都与炼油厂的作业有关。对鱼类进行了识别、计数，并检查了外部损伤情况。记录了较年长的牛头鲇的体长和体重，并对其肝脏进行了组织学检查。在上游、受影响（接收废水）和下游站点之间，鱼类的多样性和数量存在差异。在一条溪流中，观察到从上游站点采集的对照牛头鲇与在受影响站点采集的牛头鲇在肝脏病理学上存在差异，从受影响站点采集的牛头鲇中有超过50%出现了某种病理变化，其中一条出现了肝脏透明细胞灶，这在啮齿动物中被认为是一种癌前病变。这些数据表明，水中和沉积物中芳香烃的污染（可能来自炼油厂废水）与鱼类健康受损之间存在关联。
