Dybkaer R
Department of Clinical Chemistry, Frederiksberg Hospital, Denmark.
Scand J Clin Lab Invest. 1995 Apr;55(2):97-118. doi: 10.3109/00365519509089602.
Several recent documents, from international standardization bodies, present the philosophical and statistical background for understanding the components of a measured value and its uncertainty, as well as the relevant nomenclature for their description. The value is the output of a function relating values from reading, calibrator, corrections and influence quantities. The corrected value may be regarded as the sum of a true value, bias of measurement procedure, laboratory deviation, and random error; in some cases there are also biases from aberrant sample and undetected mistakes. The contributions of laboratory deviation and random error vary with the precision conditions that must be specified. The uncertainty measures are no longer a sum of systematic errors and the positive square root of quadratically added random errors. Now, the measured corrected value is the best estimate and the components of its uncertainty, one from each input, are all expressed as statistically or non-statistically derived variances that are combined according to the function relating the input values. The positive square root of the outcome is the combined standard uncertainty that is regarded as a standard deviation from which an expanded uncertainty may be obtained by multiplying with a coverage factor.
国际标准化机构最近发布的几份文件介绍了理解测量值及其不确定度组成部分的哲学和统计背景,以及用于描述它们的相关术语。该值是一个函数的输出,该函数将来自读数、校准器、修正值和影响量的值关联起来。修正值可视为真值、测量程序偏差、实验室偏差和随机误差的总和;在某些情况下,还存在异常样本偏差和未检测到的错误。实验室偏差和随机误差的贡献随必须指定的精度条件而变化。不确定度度量不再是系统误差与二次相加随机误差的正平方根之和。现在,测量的修正值是最佳估计值,其不确定度的各个分量(每个输入一个)均表示为根据与输入值相关的函数进行组合的统计或非统计得出的方差。结果的正平方根是合成标准不确定度,它被视为一种标准偏差,通过乘以覆盖因子可从中获得扩展不确定度。