成人斯蒂尔病的流行病学：法国西部一项回顾性研究对发病率的估计。
Epidemiology of adult Still's disease: estimate of the incidence by a retrospective study in west France.
作者信息
Magadur-Joly G, Billaud E, Barrier J H, Pennec Y L, Masson C, Renou P, Prost A
机构信息
Department of Internal Medicine, Nantes University Hospital, France.
出版信息
Ann Rheum Dis. 1995 Jul;54(7):587-90. doi: 10.1136/ard.54.7.587.
OBJECTIVES
To estimate the incidence of adult Still's disease (ASD) and to specify, if possible, associated factors.
METHODS
A retrospective study of the populations of the Brittany and Loire regions in west France was made from 1 January 1982 to 31 December 1991. All internal medicine and rheumatology practitioners of these regions were consulted.
RESULTS
Sixty-two (62) cases were reported (93% response). The disease incidence calculated over five years was 0.16 per 100,000 inhabitants in the study population. There was no sex bias (sex ratio 1.06 in ASD v 1.05 in the overall population. The mean age of the study population was 36 years, with two peaks of distribution at 15-25 and 36-45 years. A history of allergy was present in 23% of patients (n = 14). In two patients, it was possible to correlate an environmental allergen to exacerbation of ASD.
CONCLUSION
The yearly incidence of ASD was estimated to be 0.16 per 100,000 inhabitants. However, it was not possible to incriminate any infectious, toxic, or genetic factors in exacerbation of the disease.
目的
评估成人斯蒂尔病（ASD）的发病率，并尽可能明确相关因素。
方法
对1982年1月1日至1991年12月31日法国西部布列塔尼和卢瓦尔地区的人群进行回顾性研究。咨询了这些地区的所有内科和风湿病科医生。
结果
报告了62例病例（回复率93%）。研究人群中五年计算出的疾病发病率为每10万居民0.16例。无性别差异（ASD中的性别比为1.06，总体人群中为1.05）。研究人群的平均年龄为36岁，在15 - 25岁和36 - 45岁有两个分布高峰。23%的患者（n = 14）有过敏史。在两名患者中，有可能将环境过敏原与ASD的加重相关联。
结论
估计ASD的年发病率为每10万居民0.16例。然而，无法确定该疾病加重的任何感染、毒性或遗传因素。
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