Pe'er J, Neudorfer M, Ron N, Anteby I, Lazar M, Rosenmann E
Department of Ophthalmology, Hadassah University Hospital, Jerusalem, Israel.
Arch Pathol Lab Med. 1995 Sep;119(9):844-8.
Intraocular malignant mesenchymal tumors are very rare, and only a few case reports of such primary and metastatic tumors have been reported. We report a case of a malignant mesenchymoma involving the entire uveal tract. A 21-year-old woman presented with a tumor on the whole iris of the right eye, which caused intractable glaucoma. Upon enucleation of the eye, a very anaplastic tumor was found to occupy the whole uveal tract; its features were compatible with a tumor of mesenchymal origin, including rhabdomyosarcomatous and liposarcomatous characteristics. Choroidal osteoma was a coincidental finding. The histologic findings of the tumor were of two types of malignant mesenchymal tumors, and therefore the diagnosis of malignant mesenchymoma was made. This is to our knowledge the first tumor of its kind to be reported intraocularly.
眼内恶性间叶性肿瘤非常罕见，仅有少数关于此类原发性和转移性肿瘤的病例报告。我们报告一例累及整个葡萄膜的恶性间叶瘤病例。一名21岁女性因右眼全虹膜肿瘤就诊，该肿瘤导致难治性青光眼。眼球摘除术后，发现一个高度间变的肿瘤占据整个葡萄膜；其特征与间叶源性肿瘤相符，包括横纹肌肉瘤和脂肪肉瘤特征。脉络膜骨瘤为偶然发现。肿瘤的组织学表现为两种类型的恶性间叶性肿瘤，因此诊断为恶性间叶瘤。据我们所知，这是首例眼内报告的此类肿瘤。
