Fønnebø V
Institute of Community Medicine, University of Tromsø, Norway.
Arctic Med Res. 1995 Jul;54(3):151-4.
The association between month of birth and radiographically diagnosed bilateral arthrosis of the hip and/or knee was studied in 1405 cases at the University Hospital, University of Tromsø. In the total group no association was found in either sex for all arthrosis combined. In women with arthrosis of both hip and knee joints, however, the ratio between observed and expected showed a seasonal trend with a peak in the spring (1.48 for April births) and a low in the autumn and winter (0.39 for November births) (Test for seasonality: X2 = 9.48, d.f. = 2, p < 0.01). Low sunlight exposure prior to a crucial period in skeletal development is suggested as a possible cause.
在特罗姆瑟大学医院的1405例病例中，研究了出生月份与经影像学诊断的双侧髋关节和/或膝关节骨关节炎之间的关联。在整个研究组中，对于所有合并的骨关节炎，未发现性别与出生月份之间存在关联。然而，在患有髋关节和膝关节骨关节炎的女性中，观察值与期望值之比呈现出季节性趋势，春季达到峰值（4月出生者为1.48），秋冬季节较低（11月出生者为0.39）（季节性检验：X2 = 9.48，自由度 = 2，p < 0.01）。骨骼发育关键期之前阳光照射不足被认为是一个可能的原因。
