Silva D T, Hagan R, Sly P D
Princess Margaret Hospital, Perth, Australia.
J Paediatr Child Health. 1995 Jun;31(3):185-8. doi: 10.1111/j.1440-1754.1995.tb00782.x.
To describe the course and management of infants with neonatal chronic lung disease who were discharged home on low-flow supplemental oxygen.
Retrospective case series in Western Australia.
Fifty-six neonates born in the 6 year period 1987-92 inclusive were discharged home on supplemental oxygen. The median gestational age was 27 weeks (range 22-40), median birthweight 865 g (range 450-3350), median oxygen flow rates 125 mL/min (range 30-850). The median corrected age at discharge was 1 month (range term-9.5) and this had decreased throughout the study period. Acute hospital readmissions were common (36 of 56, 64%). The majority of these admissions were for wheezing illnesses. Three infants died. The median corrected age at weaning from day oxygen was 4 months (range term-33) and from night oxygen was 6 months (range 2-38). Monitoring of oxygen saturation in air, in low-flow oxygen and in the overnight sleep study were important non-invasive guides in deciding when patients were ready for discharge, reducing the oxygen flow rate and when oxygen could be ceased, respectively.
The home oxygen programme enables infants with neonatal chronic lung disease to be discharged home earlier, is safe, and well accepted by parents and community health care workers.
描述出院时携带低流量补充氧气回家的新生儿慢性肺病婴儿的病程及管理情况。
西澳大利亚的回顾性病例系列研究。
在1987年至1992年（含）这6年期间出生的56例新生儿出院时携带补充氧气。中位胎龄为27周（范围22 - 40周），中位出生体重865克（范围450 - 3350克），中位氧流量125毫升/分钟（范围30 - 850毫升/分钟）。出院时的中位矫正年龄为1个月（范围足月儿 - 9.5个月），且在整个研究期间有所下降。急性住院再入院情况常见（56例中有36例，64%）。这些再入院大多数是因为喘息性疾病。3例婴儿死亡。停止日间吸氧的中位矫正年龄为4个月（范围足月儿 - 33个月），停止夜间吸氧的中位矫正年龄为6个月（范围2 - 38个月）。监测空气中、低流量吸氧时以及夜间睡眠研究中的血氧饱和度分别是决定患者何时准备出院、降低氧流量以及何时可以停止吸氧的重要非侵入性指标。
家庭氧疗计划能使新生儿慢性肺病婴儿更早出院，是安全的，并且被家长和社区医护人员广泛接受。
