Bandelow B, Sievert K, Röthemeyer M, Hajak G, Rüther E
Department of Psychiatry, University of Göttingen, Germany.
Eur Arch Psychiatry Clin Neurosci. 1995;245(3):165-71. doi: 10.1007/BF02193090.
In a retrospective study 100 patients with DSM-III-R/ICD-10 panic disorder and agoraphobia (PDA) were interviewed about the psychopharmacological, psychological and 'alternative' treatments they had received in the course of their illness. Patients gave global statements about how satisfied they were with the various treatments they had experienced. Many patients received treatments that have never been investigated under controlled conditions. The most common drug treatments, in descending order, were: 48% benzodiazepines, 42% tricyclic antidepressants, 32% herbal preparations, 29% neuroleptics, 7% selective serotonin reuptake inhibitors and 6% beta blockers. Of the drug prescriptions, 63% were according to international standards. Of the neuroleptics, two-thirds (63.3%) were prescribed by nonpsychiatric physicians, and only one-third by psychiatrists (33.3%). Tricyclic antidepressants were prescribed more often by psychiatrists (64.7%) than by non-psychiatrists (31.4%). Among psychological treatments, autogenic training (43% of the patients) and psychodynamic therapy (33%) were used far more frequently than behavioural/cognitive therapy (20%). These results confirm the underutilisation of available effective treatments for panic disorder (e.g. tricyclic antidepressants or behavioural therapy) and the overutilisation of treatments without proven efficacy (e.g. herbal preparations or autogenic training). Patients were most satisfied with treatments that have been proven effective in controlled studies. Among drug treatments, benzodiazepines, selective serotonin inhibitors and tricyclic antidepressants were favoured (mean on a 0-4 scale indicating effectiveness: 2.6, 2.6 and 2.4). Neuroleptics (1.4), beta-blockers (1.0) and herbal preparations (0.9) were not rated highly effective by the patients. Among psychological treatments, patients were more satisfied with behavioural/cognitive therapy (2.6) than with psychodynamic therapies (1.5).(ABSTRACT TRUNCATED AT 250 WORDS)
在一项回顾性研究中,对100名患有DSM-III-R/ICD-10惊恐障碍伴广场恐惧症(PDA)的患者进行了访谈,了解他们在患病过程中接受的心理药物治疗、心理治疗和“替代”治疗。患者对他们所经历的各种治疗的满意度进行了总体评价。许多患者接受了从未在对照条件下进行过研究的治疗。最常用的药物治疗,按降序排列为:48%苯二氮䓬类药物、42%三环类抗抑郁药、32%草药制剂、29%抗精神病药、7%选择性5-羟色胺再摄取抑制剂和6%β受体阻滞剂。在药物处方中,63%符合国际标准。在抗精神病药中,三分之二(63.3%)由非精神科医生开具,只有三分之一由精神科医生开具(33.3%)。三环类抗抑郁药由精神科医生开具的频率(64.7%)高于非精神科医生(31.4%)。在心理治疗中,自生训练(43%的患者)和心理动力疗法(33%)的使用频率远高于行为/认知疗法(20%)。这些结果证实了惊恐障碍有效治疗方法(如三环类抗抑郁药或行为疗法)未得到充分利用,而未经证实疗效的治疗方法(如草药制剂或自生训练)却被过度使用。患者对在对照研究中已被证明有效的治疗最为满意。在药物治疗中受青睐的是苯二氮䓬类药物、选择性5-羟色胺抑制剂和三环类抗抑郁药(0至4分表示有效性的平均分:2.6、2.6和2.4)。患者对抗精神病药(1.4)、β受体阻滞剂(l.0)和草药制剂(0.9)的有效性评价不高。在心理治疗中,患者对行为/认知疗法(2.6)比对心理动力疗法(1.5)更满意。(摘要截选至250词)