Goisman R M, Warshaw M G, Peterson L G, Rogers M P, Cuneo P, Hunt M F, Tomlin-Albanese J M, Kazim A, Gollan J K, Epstein-Kaye T
Massachusetts Mental Health Center, Boston 02115.
J Nerv Ment Dis. 1994 Feb;182(2):72-9. doi: 10.1097/00005053-199402000-00002.
In a cross-sectional investigation of the properties of DSM-III-R panic disorder (PD), panic disorder with agoraphobia (PDA), and agoraphobia without history of panic disorder (AWOPD), we analyzed demographic, descriptive, comorbidity, treatment, and course data for 562 subjects with PD, PDA, or AWOPD in a multicenter anxiety-disorders study. In general, AWOPD subjects had the worst functioning and PD subjects the best, as measured by length of intake episodes, education attained, likelihood of receiving financial assistance, depressive comorbidity, and likelihood of having experienced 8 weeks symptom-free. Panic disorder with agoraphobia was the most common disorder and emerged as a condition intermediate in severity between the other two. Treatments received varied little by diagnosis. Most subjects received medication, usually benzodiazepines. Psychodynamic psychotherapy was the most frequently received psychosocial treatment; cognitive and behavioral approaches were less common. Subjects classified with AWOPD were the most likely to have received exposure therapies.
在一项对《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）中惊恐障碍（PD）、伴有广场恐怖症的惊恐障碍（PDA）以及无惊恐障碍病史的广场恐怖症（AWOPD）特征的横断面调查中，我们在一项多中心焦虑症研究中分析了562名患有PD、PDA或AWOPD的受试者的人口统计学、描述性、共病、治疗及病程数据。总体而言，按照入院时间长短、受教育程度、获得经济援助的可能性、抑郁共病情况以及症状缓解8周的可能性来衡量，AWOPD受试者功能最差，PD受试者功能最佳。伴有广场恐怖症的惊恐障碍是最常见的疾病，其严重程度介于其他两者之间。不同诊断的受试者接受的治疗差异不大。大多数受试者接受药物治疗，通常是苯二氮䓬类药物。心理动力心理治疗是最常接受的社会心理治疗；认知和行为疗法较少见。被归类为AWOPD的受试者最有可能接受暴露疗法。
