Mann L M, Woods G L
Department of Pathology, University of Texas Medical Branch at Galveston, USA.
Clin Lab Med. 1995 Jun;15(2):389-405.
The past decade has seen significant improvement in the laboratory methods for the diagnosis of viral infections. Specific antiviral agents are available for treatment of several viral infections, further increasing the need for rapid and accurate viral diagnostics. Multiple rapid direct detection methods are available commercially for many viruses. Isolation of viruses has been improved by the use of centrifugation-enhanced culture and pre-CPE detection. In the future, nucleic acid amplification techniques will also become widely available. Given limitations in resources, clinical laboratories need to critically examine the cost-effectiveness of newer methods in patient care.
在过去十年中，病毒感染的实验室诊断方法有了显著改进。有特定的抗病毒药物可用于治疗多种病毒感染，这进一步增加了对快速、准确的病毒诊断的需求。市场上有多种针对多种病毒的快速直接检测方法可供商业使用。通过使用离心增强培养和CPE前检测，病毒分离技术得到了改进。未来，核酸扩增技术也将广泛应用。鉴于资源有限，临床实验室需要严格审查新方法在患者护理中的成本效益。
