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[骨髓对骨折愈合、长骨延迟愈合及假关节的影响]

[Effect of bone marrow on healing of fractures, delayed unions and pseudoarthroses of long bones].

作者信息

Niedźwiedzki T

机构信息

III Katedry Chirurgii AM w Krakowie.

出版信息

Chir Narzadow Ruchu Ortop Pol. 1993;58(3):194-204.

PMID:7671698
Abstract

Healing of long bones after autogenic bone marrow grafting have been monitored in 96 patients aged 36.6 on an average. Bone marrow was harvested from iliac crest and after mixing it with heparin grafted transcutaneously into the fracture site in 24 fracture patients. 42 delayed unions and 30 cases of pseudoarthrosis. Pseudoarthroses were managed by bone marrow transplantation combined with the use of Zespol fixator but no intervention within pseudoarthrosis itself. In all cases union has been achieved in fractures, delayed unions and pseudoarthroses on an average 2.8, 3.2 and 3.4 months after bone marrow transplant respectively. Transplanted bone marrow proved to speed up healing process, what turned out to be especially useful in treating of delayed unions. Its combination with Zespol fixation has brought about new method of managing pseudoarthroses.

摘要

对平均年龄为36.6岁的96例患者自体骨髓移植后长骨愈合情况进行了监测。从髂嵴采集骨髓,将其与肝素混合后经皮移植到24例骨折患者的骨折部位。有42例延迟愈合和30例假关节病例。假关节采用骨髓移植联合使用Zespol固定器进行治疗,但未对假关节本身进行干预。在所有病例中,骨折、延迟愈合和假关节分别在骨髓移植后平均2.8个月、3.2个月和3.4个月实现愈合。移植的骨髓被证明能加速愈合过程,这在治疗延迟愈合中尤其有用。它与Zespol固定相结合带来了治疗假关节的新方法。

相似文献

1
[Effect of bone marrow on healing of fractures, delayed unions and pseudoarthroses of long bones].[骨髓对骨折愈合、长骨延迟愈合及假关节的影响]
Chir Narzadow Ruchu Ortop Pol. 1993;58(3):194-204.
2
[Effect of autogenic bone marrow transplantation in fractures on the course of delayed bone union healing. Part V].
Przegl Lek. 1992;49(9):294-7.
3
[Results of autogenous bone marrow grafting in disorders of bone healing and bone defectives].
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Przegl Lek. 1992;49(9):298-301.
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Judet decortication and compression plate fixation of long bone non-union: Is bone graft necessary?Judet 骨切开术和加压钢板固定治疗长骨骨不连:植骨有必要吗?
Injury. 2011 Dec;42(12):1430-4. doi: 10.1016/j.injury.2011.03.045. Epub 2011 Apr 17.
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[Effect of autogenic bone marrow transplantation into the fracture on acceleration of long bone healing. IV].
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[TGF-beta1 as a pathophysiological factor in fracture healing].转化生长因子β1作为骨折愈合中的病理生理因素
Unfallchirurg. 2007 Feb;110(2):130-6. doi: 10.1007/s00113-006-1199-x.
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J Orthop Trauma. 2013 Sep;27(9):527-33. doi: 10.1097/BOT.0b013e31828bf077.
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Application of the 'diamond concept' with fast bone marrow aspirate concentration for the treatment of medial malleolus non-union.采用快速骨髓抽吸浓缩的“钻石概念”治疗内踝骨不连。
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Clinical Results of Decortication with Bone Grafting Method versus Extracorporeal Shock Wave Treatment in Long-Bone Pseudoarthrosis.骨移植法与体外冲击波治疗长骨假关节的临床疗效比较。
Med Sci Monit. 2023 May 2;29:e939395. doi: 10.12659/MSM.939395.
2
Cell Sources for Human In vitro Bone Models.人类体外骨模型的细胞来源。
Curr Osteoporos Rep. 2021 Feb;19(1):88-100. doi: 10.1007/s11914-020-00648-6. Epub 2021 Jan 15.