5-硝基苊在沙门氏菌中的致突变性。
Mutagenicity of 5-nitroacenaphthene in salmonella.
作者信息
Yahagi T, Shimizu H, Nagao M, Takemura N, Sugimura T
出版信息
Gan. 1975 Oct;66(5):581-2.
PMID:767193
Abstract
5-Nitroacenaphthene was proved to be mutagenic on TA100 and TA98 of Salmonella typhimurium with or without metabolic activation by S-9 Mix. A possible metabolite, 5-hydroxyacenaphthene, carcinogenicity of which had not been observed, was non-mutagenic on TA100 and TA98, with or without metabolic activation.
摘要
5-硝基苊经证实，无论有无S-9混合物的代谢激活作用，对鼠伤寒沙门氏菌TA100和TA98都具有致突变性。一种可能的代谢物5-羟基苊，其致癌性尚未观察到，无论有无代谢激活作用，对TA100和TA98都无致突变性。
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