胰高血糖素与结肠。
Glucagon and the colon.
作者信息
Taylor I, Duthie H L, Cumberland D C, Smallwood R
出版信息
Gut. 1975 Dec;16(12):973-8. doi: 10.1136/gut.16.12.973.
Abstract
The effect of glucagon on human colonic myoelectrical activity is described. By means of intraluminal, serosal, and surface electrodes, recordings from all areas of the large bowel have been obtained. Glucagon inhibited both electrical and pressure rhythms in all subjects tested. Evidence is produced to suggest a direct action on colonic smooth muscle. A controlled trial using glucagon during routine barium enema examinations suggests that it may prove to be useful for hypotonic examinations of the colon where painful spasm is present.
摘要
本文描述了胰高血糖素对人体结肠肌电活动的影响。通过腔内、浆膜和表面电极，已获取了大肠所有区域的记录。在所有受试对象中，胰高血糖素均抑制了电节律和压力节律。有证据表明其对结肠平滑肌有直接作用。一项在常规钡灌肠检查中使用胰高血糖素的对照试验表明，在存在疼痛性痉挛的结肠低张检查中，它可能被证明是有用的。
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