表现为外阴肿物的卡波西肉瘤。
Kaposi sarcoma presenting as a vulvar mass.
作者信息
Macasaet M A, Duerr A, Thelmo W, Vernon S D, Unger E R
机构信息
Department of Obstetrics and Gynecology, SUNY Health Science Center, Brooklyn, USA.
出版信息
Obstet Gynecol. 1995 Oct;86(4 Pt 2):695-7. doi: 10.1016/0029-7844(95)00090-e.
BACKGROUND
Kaposi sarcoma has become a common manifestation in people with AIDS, especially men. A few reports of Kaposi sarcoma in women with AIDS have involved nongenital areas. However, of the few patients with genital Kaposi sarcoma reported in the United States, none was believed to be human immunodeficiency virus (HIV)-positive. Genital Kaposi sarcoma associated with HIV has been reported in other parts of the world.
CASE
A 29-year-old black woman presented with severe vulvar pain, vaginal discharge, and a vulvar mass. She had been diagnosed with AIDS 25 months earlier. Biopsy of the vulvar mass revealed Kaposi sarcoma; viral analysis of the tumor was positive for herpes simplex virus type 2. Sequencing of polymerase chain reaction product verified the presence of human papillomavirus 26.
CONCLUSION
We report an HIV-associated Kaposi sarcoma presenting as a vulvar mass. This report should alert health care providers to include Kaposi sarcoma in the differential diagnosis of vulvar lesions.
背景
卡波西肉瘤已成为艾滋病患者，尤其是男性患者的常见表现。少数关于艾滋病女性患者卡波西肉瘤的报道涉及非生殖器部位。然而，在美国报道的少数生殖器卡波西肉瘤患者中，无一被认为是人类免疫缺陷病毒（HIV）阳性。世界其他地区已报道了与HIV相关的生殖器卡波西肉瘤。
病例
一名29岁黑人女性因严重外阴疼痛、阴道分泌物增多及外阴肿物就诊。她在25个月前被诊断为艾滋病。外阴肿物活检显示为卡波西肉瘤；肿瘤的病毒分析显示单纯疱疹病毒2型呈阳性。聚合酶链反应产物测序证实存在人乳头瘤病毒26型。
结论
我们报告了一例表现为外阴肿物的与HIV相关的卡波西肉瘤。本报告应提醒医疗保健人员将卡波西肉瘤纳入外阴病变的鉴别诊断中。
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