Itil T, Martorano D
New York University Medical Center, NY, USA.
Psychopharmacol Bull. 1995;31(1):147-58.
Natural substances and/or their synthetically developed active ingredients are frequently used in medicine. In psychiatry, two of the most well known natural compounds are reserpine and Ginkgo biloba extract (EGb). EGb is among the most popular over-the-counter medicines in Europe and is also available in the United States, primarily in health food stores. Already the European medical community has recognized EGb as an effective compound in the treatment of cerebral insufficiency. In a pilot bioequivalency study, the effects of three different commercially available EGb products were examined. Findings indicated significant quantitative central nervous system (CNS) effects in, at least, one of the three. Furthermore, the CNS effects of Ginkgold were similar to other psychoactive compounds classified as cognitive activators. Recent studies in which EGb 761 demonstrated therapeutic effects in the treatment of dementia have earned EGb the approval of the German BGA (Bundesgesundheit Amt) for use in the treatment of dementia.
天然物质和/或其合成开发的活性成分在医学中经常被使用。在精神病学领域，两种最著名的天然化合物是利血平和银杏叶提取物（EGb）。EGb是欧洲最受欢迎的非处方药之一，在美国也有销售，主要在健康食品商店。欧洲医学界已经认可EGb是治疗脑供血不足的有效化合物。在一项初步生物等效性研究中，对三种不同的市售EGb产品的效果进行了检验。结果表明，这三种产品中至少有一种对中枢神经系统（CNS）有显著的定量影响。此外，金纳多对中枢神经系统的影响与其他被归类为认知激活剂的精神活性化合物相似。最近的研究表明，EGb 761在治疗痴呆症方面具有治疗效果，这使得EGb获得了德国联邦卫生局（BGA）批准用于治疗痴呆症。
