Pederson K, Jørgensen M, Henriksen P
Department of Veterinary Microbiology, Toyal Veterinary and Agricultural University, Frederiksberg, Denmark.
Acta Vet Scand. 1994;35(4):439-43. doi: 10.1186/BF03548320.
Lactic acid bacteria are considered indigenous members of the gastrointestinal microflora in a number of animal species ( 1977a). Some intestinal strains of lactobacilli and streptococci are aWe to adhere to stratified squamous epithelium of some animals ( 1987), in the non-secreting part of the stomach of piglets ( 1980, 1978) and rodents ( 1982), and in the crop of poultry ( 1978). The presence of lactic acid bacteria in the digestive tract is believed to be of beneficial value to the host animal ( 1989). The production of organic acids in the stomach or the crop helps maintaining a low pH which may be important for inhibiting the colonization of potentially pathogenic bacteria, particularly in the newborn animal ( 1980, 1977, 1978). The adhesion of lactobacilli to squamous epithelium is host specific: strains capable of adhering to the epithelium of piglets are usually not able to adhere in rodents or poultry and vice versa ( 1978, 1984, 1982). Adhesion of lactic acid bacterial strains to other epithelia than stratified squamous epithelium has been reported. Thus, the attachment of lactobacilli to cells from the secreting epithelium of the murine stomach ( 1979), to intestinal cells of humans ( 1987), and to columnar epithelial cells of piglets and calves ( 1983) has been demonstrated using in vitro methods. In another study the in vivo attachment of to duodenal epithelium of gnotobi-otic chickens was demonstrated 1981). Recent research indicated that in adult mink lactic acid bacteria are not indigenous members of the intestinal flora, and they do not attach to epithelium in any part of the gastrointestinal tract ( 1992). The present paper presents evidence that Gram positive cocci may colonize the gut of suckling mink kits and attach to the gut mucosa.
乳酸菌被认为是许多动物物种胃肠道微生物区系的固有成员（1977a）。一些肠道乳酸杆菌和链球菌菌株能够附着于某些动物的复层鳞状上皮（1987），如仔猪胃的非分泌部分（1980、1978）、啮齿动物（1982）以及家禽的嗉囊（1978）。消化道中乳酸菌的存在被认为对宿主动物具有有益价值（1989）。在胃或嗉囊中产生有机酸有助于维持低pH值，这对于抑制潜在病原菌的定殖可能很重要，尤其是在新生动物中（1980、1977、1978）。乳酸杆菌对鳞状上皮的附着具有宿主特异性：能够附着于仔猪上皮的菌株通常无法附着于啮齿动物或家禽，反之亦然（1978、1984、1982）。已有报道称乳酸菌菌株可附着于除复层鳞状上皮以外的其他上皮。因此，已使用体外方法证明乳酸杆菌可附着于小鼠胃分泌上皮的细胞（1979）、人类肠道细胞（1987）以及仔猪和犊牛的柱状上皮细胞（1983）。在另一项研究中，证明了[具体菌株]在无菌鸡十二指肠上皮的体内附着（1981）。最近的研究表明，成年水貂的乳酸菌不是肠道菌群的固有成员，它们不会附着于胃肠道任何部位的上皮（1992）。本文提供了证据表明革兰氏阳性球菌可能定殖于哺乳水貂幼崽的肠道并附着于肠黏膜。
